DPP-420 Industrial Blister Packing Machine
The DPP-420 is an industrial-grade flagship blister machine designed for grand-scale pharmaceutical production. Featuring a massive 420mm wide-format thermoforming station, it achieves peak industrial velocities with a multi-axis servo-driven system. Engineered for synchronized, heavy-duty cycles, the 420-series ensures a 100% hermetic seal for sensitive formulas while maximizing material utilization and lowering the Total Cost of Ownership
Grand-Format 420mm Web
Massive 420mm forming width for high-volume, multi-row batches. Independent thermal zones ensure zero-defect pocket precision for ALU-ALU & ALU-PVC.
Multi-Axis Servo Sync
High-velocity multi-axis servo integration synchronizes feeding, forming, and sealing. Delivers peak industrial output with 100% airtight, symmetrical integrity.
Heavy-Duty Vibration Control
Reinforced industrial-grade chassis eliminates mechanical vibration during 24/7 high-speed cycles, ensuring an elite, professional finish on every grand-format strip.
AI & GMP Quality Control
Fully cGMP & CE compliant with SS316L contact parts. Supports AI visual inspection and auto-waste rejection for 100% pharmaceutical regulatory compliance.





Compact Footprint
Optimized for limited cleanroom spaces and laboratory environments.
15-Min Quick Changeover
Modular design allows mold replacement in 15 mins without professional tools.
Multi-Material Compatibility
Seamlessly switch between Alu-Plastic and Alu-Alu (Cold Forming) packaging.
Working principle of blister packaging machine for clinical trials
Unwinding
Active release of PVC/ALU film with high-sensitivity tension balancing.
Pre-heating
PID intelligent temperature control for uniform material softening.
Blister Forming
Positive air pressure creates high-definition pockets (Max 26mm).
Product Feeding
Synchronized planetary feeding ensures 100% filling rate accuracy.
Heat Sealing
Rolling or flat-plate sealing for pharmaceutical-grade hermetic fuses.
Batch Coding
High-clarity mechanical embossing for expiry and batch data.
Indentation
Precisely engineered tear-lines for single-dose patient use.
Servo Traction
Servo-motor indexing ensures millimetric accuracy with zero waste.
Die Cutting
Alloy steel punching system for clean, burr-free pack edges.
Discharge
Automated output delivery ready for downstream cartoning.
Waste Reeling
Automatic scrap winding for a clean, GMP-compliant workspace.
DPP420 Industrial Encapsulation System Product Applications:

Unit Dose Packaging

PLASTIC-PAPER

Capsule Blister

Tablet Blister
Technical Data
DPP-420 Advanced Blister Packing Machine
GMP & CE COMPLIANT
ALU-PVC / ALU-ALU / PTP PRECISION
DPP-420 Technical Specifications | |
|---|---|
| Punching Frequency | 10–25 times/min |
| Max. Forming Area | 390 × 180 × 26 mm |
| Adjustable Stroke Range | 40–180 mm |
| PVC Material Specs | 0.15–0.5 × 420 mm |
| PTP ALU Specs | 0.05–0.1 × 420 mm |
| Power Requirement | 380V/220V 50Hz / 22 kW |
| Air Pressure | 0.4–0.6 Mpa |
| Cooling System | Tap water or circulating water |
| Dimensions (L×W×H) | 6000 × 950 × 2000 mm |
| Machine Weight | 2000 kg (High-Stability Chassis) |
🚀 Ultra-Wide Production Excellence
The DPP-420 is a heavy-duty flagship designed for massive throughput. Featuring a substantial 420mm web width and a 22kW power system, this 2-ton industrial workhorse provides the stability and surface area required for high-volume pharmaceutical and supplement packaging without compromising on seal integrity.
Extra-Wide 420mm Format
Utilizes a wider material feed to accommodate larger layouts and maximize output per stroke.
Extended 180mm Stroke
Highly adjustable stroke range (40-180mm) offers extreme flexibility for various blister card sizes.
High-Output Power System
Equipped with a 22kW motor system to handle heavy-duty forming and punching loads effortlessly.
Precision Material Handling
Compatible with thick PVC (up to 0.5mm) and various PTP foils for medical-grade protection.
Reinforced 6-Meter Chassis
The extended footprint ensures smooth material transition and provides ample room for auxiliary stations.
Video
Products Features

01 Precision Thermoforming
02 Customized Feeder
03 Servo-Driven Traction
04 Intelligent HMI Control
Product Details





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We are a professional manufacturer of pharmaceutical and packaging machinery. In addition to thermoforming machines,we also offer capsule filling machines, rotary tablet presses, cartoning machines, and case packers.
FAQ
The DPP-420 features a massive 420mm ultra-wide forming web, the largest in its series. It is engineered for multi-row, grand-format production, allowing manufacturers to produce massive pharmaceutical batches or large medical kits on a single synchronized platform, maximizing floor-space efficiency.
The DPP-420 delivers a punching frequency of 20–50 times per minute with a maximum forming area of 410 × 150 × 25 mm (customizable up to 50mm depth). It operates on a 15.0 kW power core and requires 0.6–0.8 MPa air pressure to maintain peak industrial velocities.
It utilizes an advanced multi-axis servo-driven synchronization system and independent thermal control zones. This ensures consistent pressure and temperature across the entire 420mm width, providing a 100% hermetic seal for ALU-ALU and ALU-PVC, even at maximum speeds.
Yes. As a flagship model, the DPP-420 is designed for Industry 4.0 integration. It supports advanced AI-driven visual inspection, automatic waste rejection, and PLC-based remote monitoring to ensure zero-defect quality and full cGMP/CE compliance.
By consolidating the output of three standard lines into one DPP-420 grand-format station, facilities can reduce labor costs by 60% and material waste by 15%. This significantly lowers the Total Cost of Ownership (TCO) while increasing daily throughput for high-volume contracts.
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